Recent Publications

PW Henderson, SP Singh, AL Weinstein, V Nagineni, DC Rafii, D Kadouch, DD Krijgh, JA Spector. Therapeutic Metabolic Inhibition: Hydrogen Sulfide Significantly Mitigates Skeletal Muscle Ischemia Reperfusion Injury In Vitro and In Vivo. Plastic and Reconstructive Surgery 2010 (in press).

PW Henderson, AL Weinstein, AM Sohn, N Jimenez, DD Krijgh, JA Spector. Hydrogen sulfide attenuates intestinal ischemia-reperfusion injury when delivered in the post-ischemic period. Journal of Gastroenterology and Hepatology 2010 (in press).

P Zawaneh, SP Singh, PW Henderson, R Padera, JA Spector, D Putnam. An injectable hydrogel for seroma prevention following radical breast mastectomy. Proceedings of the National Academy of Sciences (in press).

PW Henderson, AL Weinstein, J Sung, SP Singh, V Nagineni, JA Spector. Hydrogen sulfide attenuates ischemia-reperfusion Injury in in vitro and in vivo models of intestine free tissue transfer. Plastic and Reconstructive Surgery 2010;125(6):1670-8.

PW Henderson, GK Lewis, A Sohn, N Shaikh, AL Weinstein, W Olbricht, JA Spector. A portable high intensity focused ultrasound device for non-invasive venous ablation. Journal of Vascular Surgery 2010;51(3):707-11.

PW Henderson, DJM Kadouch, SP Singh, PN Zawaneh, J Weiser, S Yazdi, AL Weinstein, U Krotscheck, D Putnam, JA Spector. A rapidly resorbable hemostatic biomaterial based on dihydroxyacetone. Journal of Biomedical Materials Research, Part A 2010;93(2):776-82.

PW Henderson, SP Singh, D Belkin, V Nagineni, AL Weinstein, J Weissich, JA Spector. Hydrogen sulfide protects against ischemia-reperfusion injury in an in vitro model of cutaneous tissue transplantation. Journal of Surgical Research 2010 159(1):451-5.

EH Teo, KJ Cross, ED Bomsztyk, AL Weinstein, DC Lyden, JA Spector. Gene therapy in skin: choosing the optimal viral vector. Annals of Plastic Surgery 2009;62(5):576-80.

LM Bellan, SP Singh, PW Henderson, HG Craighead, JA Spector. Fabrication of an Artificial 3-Dimensional Vascular Network Using Sacrificial Sugar Structures. Soft Matter 2009;5(7):1354-7.

KJ Cross, ED Bomszyck, AL Weinstein, EH Teo, JA Spector, DC Lyden. A Novel Method for Targeted Gene Therapy in Ischemic Tissues through Viral Transfection of an Expression Cassette Containing Multiple Repetitions of Hypoxia Response Element. Plastic and Reconstructive Surgery 2009;129:76S-82S.

Recent Abstracts & Presentations

2010 Plastic Surgery Research Council (San Francisco, CA): A Sohn, PW Henderson, AL Weinstein, JA Spector. Salvage of Enteric Tissue after a Period of Critical Ischemia: Diminution of Oxidative Stress via Treatment with Hydrogen Sulfide.

DD Krijgh, D Belkin, PW Henderson, Y Zheng, LJ Bonassar, AD Stroock, JA Spector. Choosing the Optimal Tissue Regeneration Template: A Quantitative Analysis of Cellular Invasion and Migration in Integra and Strattice.

N Jimenez, PW Henderson, D Krijgh, A Sohn, JA Spector. Solving the question of protection: Hydrogen Sulfide confers protection from IRI via activation of the JAK-STAT Pathway.

N Jimenez, DD Krijgh, PW Henderson, J Ruffino, AM Sohn, JA Spector. Gasotransmitter-Mediated Mitigation of Ischemia-Reperfusion Injury in the Setting of Diabetes.

PW Henderson, V Nagineni, N Jimenez, A Sohn, D Krijgh, JA Spector. Tissue-Derived Acellular Matrices: A Novel Approach Towards the Generation of Vascularized Tissue Constructs.



2010 Academic Surgical Congress (San Antonio, TX): PW Henderson, D Belkin, Y Zheng, L Bonassar, AD Stroock, JA Spector. Defining parameters for rapid cellular invasion and vascularization in acellular hydrogel scaffolds.

DA Belkin, PW Henderson, Y Zheng, D Krijgh, L Bonassar, A Stroock, JA Spector. A mathematical histological description of the cell invasion of dermal replacement scaffolds Strattice® and Integra®.

AL Weinstein, PW Henderson, VV Nagineni, JJ Sung, JA Spector. Post-ischemic treatment with hydrogen sulfide mitigates intestinal ischemia-reperfusion injury in vivo.

PW Henderson, J Ruffino, B Wechsler, D Krijgh, H Hoffman, AL Weinstein, JA Spector. Hydrogen sulfide is protective against ischemia-reperfusion injury in chronic diabetic state.

N Jimenez, PW Henderson, J Ruffino, AL Weinstein, A Sohn, D Krijgh, JA Spector. The novel cytoprotectant hydrogen sulfide mitigates ischemia-reperfusion injury via a xanthine oxidase-mediated pathway.

PW Henderson, VV Nagineni, J Ruffino, AL Weinstein, JA Spector. Tissue-derived acellular matrices: a novel approach towards the generation of vascularized tissue constructs.

A Sohn, PW Henderson, GK Lewis, N Shaikh, W Olbricht, JA Spector. An innovative non-invasive modality for the treatment of varicose veins and other vascular anomalies.

N Jimenez, D Krijgh, PW Henderson, SP Singh, AL Weinstein, VV Nagineni, JA Spector. Salvage of the ischemic extremity: hydrogen sulfide prevents ischemia-reperfusion injury in muscle when delivered prior to revascularization.



2010 New York Regional Society of Plastic Surgeons Annual Meeting (New York, NY): PW Henderson, AM Sohn, GK Lewis, N Shaikh, W Olbricht, JA Spector. An innovative non-invasive modality for the ablation of varicose veins and other vascular malformations.

PW Henderson, LM Bellan, SP Singh, V Nagineni, HG Craighead, JA Spector. Fabrication of scalable three-dimensional microchannel networks using sacrificial microfibers.

PW Henderson, SP Singh, AL Weinstein, J Sung, V Nagineni, Jason A Spector. Hydrogen sulfide attenuates intestinal ischemia-reperfusion injury.



2010 American Society of Reconstructive Microsurgeons Annual Meeting (Boca Raton, FL): PW Henderson, Y Zheng, L Bonassar, AD Stroock, JA Spector. Optimizing neovascularization of tissue regeneration templates by rational design and microfabrication.

VV Nagineni, PW Henderson, AL Weinstein, N Shaikh, JA Spector. Tissue-derived acellular matrices: a novel approach towards the generation of vascularized tissue constructs.



2009 Biomedical Engineering Society Annual Meeting (Pittsburgh, PA): GK Lewis, W Olbricht, PW Henderson. Pocket-sized ultrasonic surgical and rehabilitation solutions: from the lab bench to clinical trials.

Y Zheng, PW Henderson, L Bonassar, JA Spector, AD Stroock. Roles of geometry and mechanics in cellular invasion and vascular angiogenesis in acellular hydrogel scaffolds.



2009 Northeastern Society of Plastic Surgeons Annual Meeting (Charleston, SC): PW Henderson, V Nagineni, AL Weinstein, SP Singh, J Ruffino, Marta Galecki, JA Spector. Pharmacological Preconditioning: Hydrogen Sulfide Protects Against Ischemia-Reperfusion Injury in an In Vitro Model of Muscle Free Tissue Transfer.

PW Henderson, Y Zheng, LJ Bonassar, AD Stroock, JA Spector. Defining Parameters for Rapid Cellular Invasion and Vascularization in Acellular Hydrogel Scaffolds.

AL Weinstein, PW Henderson, V Nagineni, JJ Sung, JA Spector. Hydrogen Sulfide Protects Against Intestinal Ischemia-Reperfusion Injury In Vivo.



2009 American College of Surgeons Surgical Forum (Chicago, IL): SP Singh, PW Henderson, AL Weinstein, V Nagineni, JA Spector. Hydrogen sulfide: a novel cytoprotectant against muscle ischemia reperfusion injury in vitro and in vivo.

AJ Reiffel, MR Kamdar, DJM Kadouch, PW Henderson, CH Rohde, JA Spector. Perioperative antibiotics in the setting of microvascular free tissue transfer: defining a standard of care.

AL Weinstein, PW Henderson, VV Nagineni, JJ Sung, JA Spector. Post-ischemic treatment with hydrogen sulfide mitigates intestinal ischemia-reperfusion injury in vivo.

N Jimenez, PW Henderson, J Ruffino, AL Weinstein, A Sohn, D Krijgh, JA Spector. The novel cytoprotectant hydrogen sulfide mitigates ischemia-reperfusion injury via a xanthine oxidase-mediated pathway.